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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE
All Species:
18.18
Human Site:
T1875
Identified Species:
44.44
UniProt:
Q07864
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07864
NP_006222.2
2286
261518
T1875
F
N
R
I
I
L
C
T
K
K
R
R
V
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543348
2273
260734
T1868
F
N
R
I
I
L
C
T
K
K
R
R
I
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF7
2283
262009
T1874
F
N
R
I
I
L
C
T
K
K
R
R
I
E
D
Rat
Rattus norvegicus
NP_001100622
1515
174729
F1138
I
C
R
A
I
Q
R
F
L
L
A
Y
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233985
2277
260654
T1870
F
N
R
I
I
L
C
T
K
K
R
R
I
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121995
2284
262166
T1874
F
N
R
L
I
L
C
T
K
K
R
R
I
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524462
2236
256683
L1855
N
L
M
R
K
M
F
L
R
I
I
A
E
F
K
Honey Bee
Apis mellifera
XP_393171
2183
252634
L1806
R
S
M
V
N
A
W
L
L
D
V
S
V
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328167
2221
254636
I1836
R
K
L
G
A
T
I
I
F
A
N
F
S
K
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21951
2222
255653
L1839
L
R
Y
H
V
H
N
L
T
K
K
A
L
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.7
N.A.
90.5
60.7
N.A.
N.A.
83.7
N.A.
80
N.A.
55.2
54.6
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
94.6
N.A.
95
63.5
N.A.
N.A.
92
N.A.
90.2
N.A.
71.9
71.5
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
20
N.A.
N.A.
93.3
N.A.
80
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
N.A.
100
N.A.
100
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
62.7
N.A.
N.A.
N.A.
60.1
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
0
0
0
10
10
20
0
0
0
% A
% Cys:
0
10
0
0
0
0
50
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
50
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
50
10
% E
% Phe:
50
0
0
0
0
0
10
10
10
0
0
10
0
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
40
60
0
10
10
0
10
10
0
40
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
50
60
10
0
10
10
20
% K
% Leu:
10
10
10
10
0
50
0
30
20
10
0
0
10
10
0
% L
% Met:
0
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
50
0
0
10
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
20
10
60
10
0
0
10
0
10
0
50
50
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
50
10
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
10
0
20
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _